Consumables[]
| Name | Icon | Type | Description | Effect | Unlock Method |
|---|---|---|---|---|---|
| Betelgeuse | 
|
Rune | Supernova! | Causes a Mama Mega explosion in the current room. |  Complete the Boss Rush as  Andromeda.
|
| Alpha Centauri | 
|
Rune | Stellar formation | Consumes all items and pickups in the room.
Each pickup has a 50% chance of turning into a random wisp. Pedestal items grant a permanent star wisp that has a unique effect based on the quality of the item consumed. |
Complete the Boss Rush as Andromeda.
|
| Sirius |
|
Rune | Ever bright |  Overcharges all your active items.
|
 Complete the Boss Rush as  Tainted Andromeda.
|
| Soul of Andromeda | 
|
Soul Stone | Reach for the stars | Teleports you to an  Abandoned Planetarium.
|
 Defeat Hush as Tainted Andromeda.
|
| XXII - The Unknown | 
|
Card | Untold answers | Activates a random tarot card effect, normal or reversed. |  Defeat Ultra Greedier as Tainted Andromeda.
|
Misc.[]
| Name | Appearance | Type | Effect | Unlock Method |
|---|---|---|---|---|
| Spode |  |
Transformation | Collecting 3 Zodiac or Planetarium items grants flight, -0.4 shot speed down, and tears have a chance to spawn additional star tears that have homing, spectral, and deal 1/4 of your current damage.
The star tears also inherit most tear effects. |
 Earn all Completion Marks as Andromeda.
|
| Wisp Wizard |  |
Beggar | Takes coins and has a chance to pay out with a normal wisp, random wisp, trinket from its own pool, or a Zodiac item. |  Defeat Mega Satan as Tainted Andromeda.
|
| Abandoned Planetarium |  |
Room | A special room that can contain Zodiac items or different kinds of pickups and rewards. | N/A |